Biotech
Biotechnology explained: gene editing, cell and gene therapy, synthetic biology, diagnostics and the companies and papers shaping the field.
How GLP-1 Drugs Are Made, and Why Supply Ran Short
Semaglutide starts in yeast, tirzepatide is built chemically, and sterile filling capacity was the real choke point. A look at both routes,…
In Vivo Gene Editing in October 2026: What the Human Data Actually Show
One phase 3 win in hereditary angioedema, early cholesterol and AATD data, and a fatal liver event in a paused trial: a…
Soil Microbiome Products in 2026: Four Companies, Their Claims, and the Missing Evidence
Seed-applied microbes are now a product category. Four September 2026 announcements, the numbers each company reported, and the evidence a careful reader…
Newborn Genome Sequencing: What GUARDIAN and England’s Generation Study Have Reported So Far
Two large programs are testing whether a baby's genome can catch treatable conditions that heel-prick screening misses. Here are the published numbers…
Self-Driving Labs: What Autonomous Experiments Have Actually Delivered
Three peer-reviewed self-driving lab results, from A-Lab to autonomous enzyme engineering, with the numbers, the caveats and what still needs human hands.
AI-Designed Drugs in Clinical Trials: What Has Actually Been Shown
Rentosertib began phase 3 in September 2026, but no AI-designed drug has completed one. Here is what the trials, registries and success-rate…
Biosimilar Manufacturing Explained: Why Copies of Biologics Are Never Identical
A biosimilar can be highly similar to its reference biologic but never identical. How the drugs are made, what regulators compare, and…
AlphaFold Structure Prediction in Practice: What It Does and Where It Fails
AlphaFold predictions are used daily in labs, yet AlphaFold 3 struggles with moving proteins, RNA and drug potency. A question-by-question guide to…
Epigenetic Clocks Explained: What They Measure and What Longevity Trials Can Actually Show
Epigenetic clocks turn DNA methylation into an age estimate. This explainer compares the main clocks, the CALERIE result, and why validation as…
Lipid Nanoparticles vs Viral Vectors: How Gene Editors Reach the Right Cells
Delivery is the bottleneck of gene editing. A sourced comparison of lipid nanoparticles and viral vectors, their limits, and recent advances reaching…