AI-Designed Drugs in Clinical Trials: What Has Actually Been Shown
Rentosertib began phase 3 in September 2026, but no AI-designed drug has completed one. Here is what the trials, registries and success-rate data actually show.
Peter Kalafatis
X Money Creator Payouts: What Instant US Payments Change
X Money creator payouts became the only payout route for US creators on September 2, 2026, when X announced that all US creator payments would…
Biosimilar Manufacturing Explained: Why Copies of Biologics Are Never Identical
A biosimilar can be highly similar to its reference biologic but never identical. How the drugs are made, what regulators compare, and what the FDA’s…
Mars Organic Carbon in the Bright Angel Rocks: What SHERLOC Measured and What It Cannot Say
Perseverance’s SHERLOC mapped macromolecular carbon across rocks in Jezero crater’s Bright Angel formation. Here is what was measured, why the origin is open and what…
AlphaFold Structure Prediction in Practice: What It Does and Where It Fails
AlphaFold predictions are used daily in labs, yet AlphaFold 3 struggles with moving proteins, RNA and drug potency. A question-by-question guide to uses and limits.
Bilayer SnTe Is the 2D Topological Crystalline Insulator Theorists Waited a Decade For
Two layers of tin telluride on niobium diselenide gave physicists the first experimental 2D topological crystalline insulator. Here are the build specs, the strain math…
Dog Epigenetic Clock Study: Why Big Breeds Age Faster
A dog epigenetic clock built from 894 dogs in Science shows large breeds accumulate DNA methylation changes faster. Mechanism, numbers and limits.
Framework Laptop 13 Pro Review: The Repairable Laptop Grows Up, and the Price Tag Comes With It
Seven published reviews, one repairable laptop, and a memory shortage that rewrote the price tag. Here is where the Framework Laptop 13 Pro stands.
Epigenetic Clocks Explained: What They Measure and What Longevity Trials Can Actually Show
Epigenetic clocks turn DNA methylation into an age estimate. This explainer compares the main clocks, the CALERIE result, and why validation as a trial endpoint…
iFixit Mako Driver Kit Review: A 64-Bit Set That Earns Its Price
iFixit’s 64-bit Mako kit is the set most roundups rank first. It costs more than generic sets; here is where it justifies that and where…