Gene Editing
In Vivo Gene Editing in October 2026: What the Human Data Actually Show
One phase 3 win in hereditary angioedema, early cholesterol and AATD data, and a fatal liver event in a paused trial: a…
Lipid Nanoparticles vs Viral Vectors: How Gene Editors Reach the Right Cells
Delivery is the bottleneck of gene editing. A sourced comparison of lipid nanoparticles and viral vectors, their limits, and recent advances reaching…
Personalized Gene Editing After Baby KJ: From One Patient to a Possible Pathway
A timeline of personalized gene editing: baby KJ's custom base editor, the FDA's plausible mechanism draft guidance, and the prime editing platform…
Off-Target Effects in Gene Editing: How Scientists Find and Measure Them
Off-target effects are unintended gene edits. Here is how prediction, test-tube assays, cell-based methods and deep sequencing find them, and why no…
CRISPR-Cas9, Base Editing and Prime Editing: What Each Tool Actually Changes
Cas9 cuts, base editors swap a letter, prime editors rewrite short stretches. A plain comparison of what each tool does to DNA…
How CRISPR Works: Gene Editing Explained, and What It Has Done
CRISPR began as a bacterial immune system. This article explains the mechanism, the first approved therapy, a 2025 personalized treatment, and the…